Best Diagnosis Methods for Covid 19
Protect yourself with the covid test for travel and for reassuring your health conditions. Wear a mask and stay 6 feet away from others; try to avoid public gathering as much as possible and also poor ventilation. Don’t forget to wash your hands regularly.
Two separate tests are available for the diagnosis of the COVID- 19 virus and if anyone has gotten infected or not. These two types of diagnosis refer to the different phases of SARS-CoV2 that a patient may encounter:
Direct Tests- Typically used for the detection of the presence of virus in the patient.
Indirect Tests- These tests show that if a patient has been infected via antibodies developed against the virus or not.
You can book covid test Brampton today at Medcare Diagnosis centre, and the tests will be carried out, and reports will be given out within 24–72 hours.
Techniques for an Early Diagnosis of COVID- 19
Direct Tests
Detection through RNA Using PCR
In this microbiological diagnosis of COVID- 19, the detection of the SARS-CoV2 RNA in the respiratory samples is considered for reference.
Pros
This test comes with the highest sensitivity and more specificity for virus detection.
RNA can be detected two days before symptoms have started to appear. It is necessary because, after the first phase of symptoms, the viral load starts increasing rapidly and gradually becomes undetectable after 2–3 weeks.
It helps in virus detection in asymptomatic patients, and PCR can remain positive for 30 days in severe cases.
It also confirms the virus presence in patients who had COVID-19.
Cons
Advanced level equipment is required for instant covid test Brampton- it’s a laborious technique and needs level 2 Biosafety rooms and specialised staffs.
Detection through Antigen
For instant covid test results Niagara, this direct technique can also be used by detecting virus proteins, otherwise known as Antigens.
This detection is performed using respiratory samples of patients and an Antigen-Antibody reaction.
Cons
It is quite inadequate as a diagnosis technique, and almost less than 50% of patients are detected in real life.
2. Indirect Technique
Detection of Antibodies in Blood Samples
Currently, it comes under rapid technique and centered on greater specificity and sensitivity — it was proposed as diagnosis of past infections as for the cases running for more than a week.
IgM — the presence appears between 7–10 days before symptoms; gradually starts decreasing post 20 days and then disappears.
IgG runs favorable from 14–20 days and stays for a longer time.
These serological tests are only possible when the patient is in the recovery phase, and the major clinical interventions have already gone.
Pros
These are more theoretically proven Immunoglobulin kinetics and very useful in identifying at what stage the patient is.
Cons
Have nothing to do with early diagnosis, and the test gives positive only after 7 to 14 days after symptoms.
FDA has warned about the false results.
Every individual produces antibodies differently after a corona virus infection, and also it takes longer to occur or may not happen with the same conditions. And it may give out false negatives.
3. Combination of Both Techniques
The combination of PCR and serological tests can work out for the better. The reference yesterday for COVID-19 identification remains RT-PCR, but antibody detection can also be counted as applicable for cases of acute infection and epidemiological causes.
The combination of PCR and Serology will help us in categorizing patients according to the risk of infection by the SARS Cov2 virus:
An infected patient- Positive PCR
A patient who is at risk: Negative PCR and Negative IgG
Patient with possible immunization: Negative PCR and positive IgG.
Medcare Diagnostics want to warn you against the interpretation of serological tests, and they must be carried out with utmost caution. As there are certain limitations, the evaluation will be considered according to the patient clinical situation, and the RT-PCR test results can work as references.
There is no scientific evidence witnessed that IgG shows the immunization against the reinjection against COVID-9 virus.
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